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Cetirizine-Pseudoephedrine

Pronounced

"sue-doh-eff-ED-rin/seh-TEER-ah-zeen"

Common brand names:

Reactine Complete

Uses

This medication is used to relieve allergy symptoms such as watery eyes, runny/stuffy nose, itching eyes/nose, and sneezing. It contains 2 medications: cetirizine and pseudoephedrine. Cetirizine is an antihistamine and works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Pseudoephedrine is a decongestant and works by narrowing the blood vessels in the nose to decrease swelling and congestion.

This medication is not recommended for use in children under 12 years of age due to the large amount of pseudoephedrine in it.

How to Use This Medication

If you are taking the over-the-counter product to self-treat, read all directions on the product package before taking this medication. If you have any questions, consult your pharmacist. If your doctor has prescribed this medication, take it as directed with or without food, usually twice daily (every 12 hours).

Swallow the tablets whole. Do not crush or chew the tablets. Doing so can release all of the drug at once, increasing the risk of side effects.

The dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this medication more often than directed.

Tell your doctor if your symptoms do not improve after 1 week, if they worsen, or if they occur with a fever.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

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Information expires December 2025.