Eliglustat
Pronounced
"EL-i-GLOO-stat"
Common brand names:
Cerdelga
Uses
This medication is used for long-term treatment of a certain rare genetic problem (Gaucher's disease). Eliglustat works by decreasing the amount of a certain natural fatty substance (glucosylceramide) that builds up due to this condition. This can improve symptoms of Gaucher's disease, such as bruising, tiredness, pain in the joints/bones, and a swollen liver/spleen.
How to Use This Medication
Read the Medication Guide provided by your pharmacist before you start taking eliglustat and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. The manufacturer directs to swallow the capsules whole, preferably with water, and not to open, crush, or dissolve the capsules before swallowing. However, other similar drugs (immediate-release capsules) can be opened, and the contents may be sprinkled on or mixed in food. Follow your doctor's directions on how to take this medication. If you are also using enzyme replacement treatment (such as imiglucerase, velaglucerase alfa, or taliglucerase alfa), you may take this medication 24 hours after your dose of the enzyme replacement treatment.
Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.
The dosage is based on your medical condition, response to treatment, lab tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
Tell your doctor if your condition does not improve or if it worsens.
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Information expires December 2025.