Read the Patient Information Leaflet if available from your pharmacist before you start taking indinavir and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with a full glass of water (8 ounces or 240 milliliters) on an empty stomach (at least 1 hour before or 2 hours after food) as directed by your doctor, usually 3 times daily. If upset stomach occurs, you may take it with other liquids (such as non-fat milk, apple juice, coffee, tea) or with a light meal (such as dry toast with jelly, corn flakes with non-fat milk and sugar). Avoid taking this medication with a meal high in calories, fat, and protein since this may decrease its effect. If you are directed to take ritonavir with this medication, take them both at the same times.

To help decrease the risk of kidney stones while taking indinavir, drink at least 6 full glasses (8 ounces or 240 milliliters each) of water or other liquids throughout the day.

The dosage is based on your weight, medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

For the best effect, take this medication at evenly spaced times. To help you remember, take this medication at the same times every day.

It is very important to keep taking this medication (and other HIV medications) exactly as prescribed by your doctor. Do not take more or less of this drug than prescribed or stop taking it (or other HIV medicines) even for a short time unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause the amount of virus to increase, make the infection more difficult to treat, or worsen side effects.