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Lemborexant

Pronounced

"LEM-boe-REX-ant"

Common brand names:

Dayvigo

Uses

This medication is used to treat a certain sleep problem (insomnia). It may help you fall asleep, and help you stay asleep longer, so you can get a better night's rest. Lemborexant belongs to a class of drugs known as sedative-hypnotics.

If your insomnia continues for longer than 7 to 10 days after starting treatment, talk to your doctor to see if you need other treatment.

How to Use This Medication

Read the Medication Guide provided by your pharmacist before you start taking lemborexant and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take lemborexant by mouth as directed by your doctor, usually right before you get into bed. This medication can be taken with or without food, but it may take longer to work if you take it with or right after a meal. Do not take this medication with alcohol or with other drugs that help you sleep.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Do not take a dose of this drug unless you have time for a full night's sleep of at least 7 hours. If you have to wake up before that, you may have trouble safely doing anything that needs alertness, such as driving or operating machinery. (See also Precautions section.)

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

Do not increase your dose, take it more often, or use it for longer than prescribed. Your condition will not improve any faster and your risk of side effects will increase.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.

Tell your doctor if your condition lasts after 7 to 10 days, or if it gets worse.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

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Information expires December 2025.