Nicotine (Polacrilex)

This form:

Pronounced

"NICK-oh-teen"

Common brand names:

Nicorette

Uses

This medication can help you quit smoking by replacing the nicotine in cigarettes. The nicotine in tobacco is an important part of cigarette addiction. When you stop smoking, your nicotine levels drop quickly. This drop can cause withdrawal symptoms such as craving tobacco, nervousness, irritability, headache, weight gain, and difficulty concentrating.

Stopping smoking is hard and your chance of success is best when you are ready and have made a commitment to quit. Nicotine replacement products are part of a total stop-smoking program that includes behavior change, counseling, and support. Smoking causes lung disease, cancer, and heart disease. Stopping smoking is one of the most important things you can do to improve your health and live longer.

How to Use This Medication

If you are using the over-the-counter product, read all directions on the product package before using this medication. If your doctor has prescribed this medication, read the Patient Information Leaflet if available from your pharmacist before you start using this product and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Do not eat or drink anything for 15 minutes before or during use of the gum. Do not use if the individual wrapper is open or damaged.

Start this medication on your quit (smoking) day. Chew a piece of gum when you feel the urge to smoke. Chew the gum very slowly until it tingles, then move it to the space between your cheek and gum. Keep it there until it stops tingling. When the tingle is gone, begin chewing again until the tingle returns. Most of the nicotine will be gone after 30 minutes. Do not use more than 1 piece of gum at a time. You may also use this product on a regular schedule as well as at times when you have the urge to smoke. The best dose for you is the dose that decreases the urge to smoke without side effects from too much nicotine. Your dose will need to be adjusted to your needs, including your smoking history and medical condition.

For the first 6 weeks, use at least 9 pieces each day. If you still have a strong urge to smoke, you can use a second piece of gum within 1 hour. Do not continuously use 1 piece right after another. Doing so will increase side effects such as hiccups, nausea, or heartburn. Most people use about 9 to 12 pieces of gum per day during the first month of treatment. Do not chew more than 24 pieces of gum a day.

After you have stopped smoking and you have reached the best dose and schedule for you, continue at that dose. Start to lower your dose after 6 weeks or as directed by your doctor until you are no longer smoking and no longer need nicotine replacement. It is important to complete the treatment with this medication (12 weeks). If after the treatment period, you still feel the need to use this medication to prevent you from smoking, talk to your doctor.

If you suddenly stop using this medication, you may have withdrawal symptoms (such as tobacco cravings, nervousness, irritability, headache). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used nicotine for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal.

Some smokers are unsuccessful the first time they try to quit. You may need to stop using this product and try again later. Many people who cannot quit the first time are successful the next time.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

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Information expires December 2025.