Semaglutide
Pronounced
"SEM-a-GLOO-tide"
Common brand names:
Ozempic
Uses
Semaglutide is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Semaglutide is also used in people with type 2 diabetes and heart disease to lower the risk of death from heart attack or stroke.
Semaglutide is similar to a natural hormone in your body (incretin). It works by causing insulin release in response to high blood sugar (such as after a meal) and decreasing the amount of sugar your liver makes.
If you use insulin, semaglutide is not a substitute for insulin treatment.
How to Use This Medication
Read the Medication Guide and Instructions For Use provided by your pharmacist before you start using semaglutide and each time you get a refill. Ask your health care professional how to prepare and use this medication. If you have any questions, ask your doctor or pharmacist.
Inject this medication under the skin as directed by your doctor, usually once every 7 days. The injection is given in the thigh, abdomen, or upper arm. This medication may be used with or without meals. The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.
Before using, check this product for particles or discoloration. If either is present, do not use the liquid. Before injecting each dose, clean the skin you are going to inject into (the injection site) with rubbing alcohol. Change the injection site each time to lessen injury under the skin. To lessen bruising, do not rub the injection site after a shot. Learn how to store and discard medical supplies safely.
Use this medication regularly to get the most benefit from it. Remember to use it every 7 days. If needed, the day of weekly use may be changed as long as the time between two doses is at least 2 days. It may help to mark your calendar with a reminder. Carefully follow the medication treatment plan, meal plan, and exercise program your doctor has recommended.
Tell your doctor if your condition does not get better or if it gets worse (your blood sugar is too high or too low).
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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.
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Information expires December 2025.