Valproic Acid

Pronounced

"val-PRO-ate SO-dee-um"

Common brand names:

Depakene

Uses

This medication is used to treat seizure disorders, mental/mood conditions (such as manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

How to Use This Medication

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking valproate sodium and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor. You may take it with food if stomach upset occurs. Use a specially marked device to measure the correct amount of medication. Valproate sodium syrup should not be mixed with carbonated drinks because it may irritate the mouth and throat.

The dosage is based on your age, weight, medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day to keep the amount of medication in your blood constant.

If this medication is used for seizures, do not stop taking it without consulting your doctor. Your condition may become worse if the drug is suddenly stopped. Your dose may need to be gradually decreased.

This medication does not relieve acute migraine headaches. Take other medications as directed by your doctor for acute attacks.

Tell your doctor if your condition does not improve.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

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Information expires December 2025.