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Velaglucerase Alfa

Pronounced

"VEL-a-GLOO-ser-ase Al-fa"

Common brand names:

VPRIV

Uses

Velaglucerase alfa is used to treat a certain rare genetic problem (Gaucher disease). Velaglucerase alfa replaces a certain natural substance (an enzyme called glucocerebrosidase) that is missing in people with Gaucher disease.

This medication improves blood, bone, liver, and spleen problems caused by Gaucher disease. Velaglucerase alfa does not correct the genetic problem, and treatment must be continued for life.

How to Use This Medication

This medication is given by injection into a vein by a health care professional. It is given as directed by your doctor, usually once every 2 weeks. It is injected slowly into a vein over 1 hour. The dosage and treatment schedule are based on your medical condition, weight, and response to treatment.

Tell your doctor if your condition lasts or gets worse. Blood, liver, and spleen problems usually improve in the first year of treatment. It may take 2 to 3 years of treatment to see the full benefit to your bones.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

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Information expires December 2025.