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Vigabatrin

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Pronounced

"vye-GAB-uh-trin"

Common brand names:

Sabril

Uses

This medication is used in combination with other medications to treat seizure disorders (epilepsy). Vigabatrin decreases the number of seizures in adults and children who have not been able to control their seizures with other treatment. Vigabatrin is an anticonvulsant. It is thought to work by stopping the breakdown of a natural calming substance (GABA) in the brain.

How to Use This Medication

Read the Medication Guide provided by your pharmacist before you start taking vigabatrin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually twice a day.

The dosage is based on your medical condition and response to treatment. Children's dosage is also based on weight. Your doctor may direct you to take a low dose at first, gradually increasing the dose to lower the chance of side effects such as drowsiness and confusion. Your doctor will adjust your dose to find the best dose for you. Follow your doctor's directions carefully.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased. Do not stop taking this medication without consulting your doctor. Your seizures may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

Tell your doctor if your seizures worsen or have not improved within 3 months.

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Information expires December 2025.