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Ziconotide

Pronounced

"zico-NO-tide"

Uses

This medication is a non-opioid pain reliever that is used to treat ongoing pain when other treatments or medications cannot control your pain. Ziconotide works by blocking the nerves in the spinal cord that send pain signals. It decreases ongoing pain caused by cancer, AIDS, failed back surgery, multiple sclerosis, neuropathy, and other causes.

How to Use This Medication

Read the instruction manual and directions that come with your infusion pump. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection as directed by your doctor, usually continuously into area around the spinal cord (intrathecal) using a small pump. To decrease the risk of side effects, treatment is usually started slowly and then gradually increased to the best dose for you. The dosage is based on your medical condition and response to treatment.

This medication should not be given into a vein or under the skin. It can cause fainting due to a dangerous drop in blood pressure if it is accidentally given into a vein.

If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.

To prevent infection, learn how to handle the infusion pump, and learn proper care of the injection site. Call your doctor right away if there is any sign of infection around the injection site (such as swelling, redness, tenderness).

Contact your doctor or pharmacist to set up a schedule for refilling your pump.

Tell your doctor if your pain lasts or gets worse.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

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Information expires December 2025.