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Betaine Hydrochloride

Also indexed as:Betaine HCl, Gastric Acid, Hydrochloric Acid, Stomach Acid
Betaine Hydrochloride: Main Image

Betaine hydrochloride is an acidic form of betaine, a vitamin-like substance found in grains and other foods. Betaine hydrochloride is recommended by some doctors as a supplemental source of hydrochloric acid for people who have a deficiency of stomach acid production (hypochlorhydria).

  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

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For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Used for AmountWhy
Acne Rosacea
Refer to label instructions 1 star[1 star]
Hydrochloric acid and vitamin B complex improved some cases of rosacea in people with low stomach acid. Take only under the supervision of a healthcare practitioner.
Allergies and Sensitivities and Food Allergies
Refer to label instructions 1 star[1 star]
Hydrochloric acid secreted by the stomach helps to digest protein, and may theoretically help break down food allergens to smaller molecules that are not allergenic.
Asthma
Refer to label instructions 1 star[1 star]
Used under medical supervision, betaine HCl may help restore stomach acid levels and improve asthma symptoms.
Chronic Candidiasis
Refer to label instructions 1 star[1 star]
Betaine hydrochloride is a type of digestive enzyme that inhibits the overgrowth of candida and prevents it from becoming established in the small intestine.
Dermatitis Herpetiformis
Refer to label instructions 1 star[1 star]
To correct the low stomach acid that often occurs with DH, some doctors recommend betaine HCI, a source of hydrochloric acid.
Gallstones
Refer to label instructions 1 star[1 star]
People with gallstones may have insufficient stomach acid and may benefit from supplementing with betaine HCI.
Gastroesophageal Reflux Disease
Refer to label instructions 1 star[1 star]
Hydrochloric acid is sometimes recommended by practitioners of natural medicine in the hope that improved digestion will help prevent reflux.
Hives
Refer to label instructions 1 star[1 star]
Lack of hydrochloric acid (HCl) secretion by the stomach may contribute to chronic hives related to food allergies. Supplementing with betaine HCI, which contains hydrochloric acid, may help.
Indigestion, Heartburn, and Low Stomach Acidity
Consult your doctor 1 star[1 star]
Supplementing betaine hydrochloride with meals may improve digestion in people who have been diagnosed with low stomach acid (hypochlorhydria).
Rheumatoid Arthritis
Refer to label instructions 1 star[1 star]
When stomach acid is low, supplementing with betaine HCl can reduce food-allergy reactions and help some people with rheumatoid arthritis.
Vitiligo
Refer to label instructions 1 star[1 star]
Lack of stomach acid may play a role in vitiligo. Supplementing with betaine HCL may help repigment the skin.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.