Branched-Chain Amino Acids
The branched-chain amino acids (BCAAs) are leucine, isoleucine, and valine. BCAAs are considered essential amino acids because human beings cannot survive unless these amino acids are present in the diet.
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
This supplement has been used in connection with the following health conditions:
| Used for | Amount | Why |
|---|---|---|
Liver Cirrhosis | At least 5 grams daily, up to 0.24 grams per 2.2 lbs (1 kg) body weight per day |  [2 stars] Under a doctor’s supervision, supplementing with branched-chain amino acids may correct an imbalance of amino acids and improve cirrhosis symptoms. |
Phenylketonuria | Take under medical supervision: 150 mg daily per 2.2 lbs (1 kg) of body weight each of valine and isoleucine, and 200 mg daily per 2.2 lbs (1 kg) of body weight of leucine | [2 stars] Regular use of branched-chain amino acids (BCAAs) may improve mental functioning. |
Athletic Performance and Mental Decline During Exercise at Extreme Temperature | Refer to label instructions |  [1 star] Some research has shown that branched-chain amino acids help prevent muscle loss at high altitudes, prolong endurance performance in the heat, and improve exercise-induced declines in mental functioning.
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Athletic Performance and Post-Exercise Infection at Extreme Temperature | Refer to label instructions | [1 star] Some research has shown that branched-chain amino acids may support immune fuction and improve infection at high altitudes and prolong endurance performance in the heat.
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Tardive Dyskinesia | Refer to label instructions | [1 star] Supplementing with branched-chain amino acids may reduce excess phenylalanine in people with tardive dyskinesia. |
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.