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Coenzyme Q10

Also indexed as:CoQ10, Ubiquinol
Coenzyme Q10: Main Image

Coenzyme Q10 (CoQ10) is also called ubiquinone, a name that signifies its ubiquitous (widespread) distribution in the human body. CoQ10 is used by the body to transform food into adenosine triphosphate (ATP), the energy on which the body runs.

  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Used for AmountWhy
Angina
150 mg daily3 stars[3 stars]
CoQ10 contributes to the heart’s energy-making mechanisms. Angina patients given CoQ10 have experienced greater ability to exercise without chest pain.
Athletic Performance
Refer to label instructions 2 stars[2 stars]
Strenuous physical activity lowers blood levels of coenzyme Q10 (CoQ10). A few studies have reported that CoQ10 supplementation benefitted some trained athletes.
Cardiomyopathy
100 to 150 mg daily2 stars[2 stars]
Most studies using coenzyme Q10 in treating cardiomyopathy have shown positive results, including improved quality of life, heart function tests, and survival rates.
Congestive Heart Failure
0.9 mg daily per pound of body weight with a doctor's supervision 2 stars[2 stars]
CoQ10 enhances the production of energy in the heart muscle and has been reported to help people with CHF, sometimes dramatically.
Fibromyalgia
Refer to label instructions 2 stars[2 stars]
In a preliminary trial, headaches and overall symptoms in people with fibromyalgia significantly improved after supplementing with coenzyme Q10.
Gingivitis
50 to 60 mg daily2 stars[2 stars]
Supplementing with CoQ10 may reduce gingivitis symptoms and repair damaged gum tissues.
Halitosis and Gum Disease
50 to 60 mg daily2 stars[2 stars]
Coenzyme Q10 is often recommended by doctors to help prevent and treat periodontitis.
Hypertension
100 mg twice per day 2 stars[2 stars]
Taking coenzyme Q10 may help lower high blood pressure.
Macular Degeneration

(Acetyl-L-Carnitine, Fish Oil)
Follow label directions2 stars[2 stars]
In one study, supplementing with a proprietary blend of acetyl-L-carnitine, fish oil, and coenzyme Q10 improved visual function in people with macular degeneration.
Metabolic Syndrome
30 to 200 mg daily2 stars[2 stars]
A small body of clinical evidence suggests coenzyme Q10 may improve insulin sensitivity, glucose and lipid metabolism, and blood pressure in those with metabolic syndrome.
Migraine Headache
100 to 150 mg daily2 stars[2 stars]
In a preliminary trial, supplementation with coenzyme Q10 for three months reduced the average number of days with migraine headaches by 60%.
Neuropathy
400 mg daily2 stars[2 stars]
There is little evidence that coenzyme Q10 improves nerve function and eases symptoms of diabetic neuropathy.
Preeclampsia
200 mg per day 2 stars[2 stars]
In a double-blind study at women who were at high risk of developing preeclampsia, supplementing with coenzyme Q10 reduced the incidence of preeclampsia by 44%.
Type 1 Diabetes
100 mg daily2 stars[2 stars]
Supplementing with CoQ10 may improve blood sugar metabolism.
Type 2 Diabetes
100 to 200 mg daily2 stars[2 stars]
Supplementing with CoQ10 may improve blood glucose control, insulin sensitivity, and cardiovascular health.
Alzheimer’s Disease

(Iron, Vitamin B6)
Refer to label instructions 1 star[1 star]
A combination of coenzyme Q10, iron (sodium ferrous citrate), and vitamin B6 may improve mental status in people with Alzheimer’s disease.
Chronic Obstructive Pulmonary Disease
Refer to label instructions 1 star[1 star]
CoQ10 levels have been found to be low in people with COPD. Supplementing with CoQ10 improved blood oxygenation, exercise performance, and heart rate in one study.
HIV and AIDS Support
Refer to label instructions 1 star[1 star]
In one trial, people with HIV who took CoQ10 experienced no further infections for up to seven months, and counts of infection-fighting white blood cells improved in some cases.
Male Infertility
Refer to label instructions 1 star[1 star]
CoQ10 is a nutrient used by the body to produce energy. While its exact role in the formation of sperm is unknown, even small amounts appear to increase sperm count and motility.
Parkinson’s Disease
1,200 mg a day1 star[1 star]
In a double-blind trial, coenzyme Q10 given to people with early Parkinson's disease significantly slowed the progression of the disease.
Tinnitus
Refer to label instructions 1 star[1 star]
For people who are deficient in CoQ10, supplementing with the nutrient may improve tinnitus.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.