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Green-Lipped Mussel

Also indexed as:Green Lipped Sea Mussel
Green-Lipped Mussel: Main Image

Green-lipped mussel (Perna canaliculus) is a New Zealand shellfish, from which an extract has been shown to be useful in the treatment of rheumatoid arthritis (RA) and osteoarthritis (OA).

  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Used for AmountWhy
Asthma
50 mg of omega-3 fatty acids twice per day2 stars[2 stars]
In a study of people with asthma, supplementing with a proprietary extract of New Zealand green-lipped mussel (Lyprinol) significantly decreased wheezing and improved airflow.
Osteoarthritis
1,050 to 2,100 mg daily of freeze-dried powder or 210 mg daily of lipid extract2 stars[2 stars]
New Zealand green-lipped mussel supplements have been shown in various studies to reduce joint tenderness and stiffness and improve pain, including knee pain in people with osteoarthritis.
Rheumatoid Arthritis
1,050 to 2,100 mg daily of freeze-dried powder or 210 mg daily of lipid extract2 stars[2 stars]
Supplementing with New Zealand green-lipped mussel may improve rheumatoid arthritis symptoms, including joint tenderness and morning stiffness.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.