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Drug

Chlorhexidine

Common brand names:

Peridex, PerioGard

Chlorhexidine is a mouthwash used to prevent and treat the redness, swelling, and bleeding gums associated with gingivitis. It is classified as an antimicrobial drug. No interactions are listed as it is not used internally.

Summary of Interactions with Vitamins, Herbs, & Foods

  • Negative Interactions

    2
    • Chlorhexidine

      Coffee

      Potential Negative Interaction

      Controlled studies show that drinking coffee and tea enhances the tooth-staining effect of chlorhexidine. People using chlorhexidine may prevent tooth staining if they consume coffee or tea an hour before or after using the drug, or if they avoid these beverages altogether.

      Coffee
      Chlorhexidine
      ×
      1. Leard A, Addy M. The propensity of different brands of tea and coffee to cause staining associated with chlorhexidine. J Clin Periodontol 1997;24:115-8.
    • Chlorhexidine

      Tea

      Potential Negative Interaction

      Controlled studies show that drinking coffee and tea enhances the tooth-staining effect of chlorhexidine. People using chlorhexidine may prevent tooth staining if they consume coffee or tea an hour before or after using the drug, or if they avoid these beverages altogether.

      Tea
      Chlorhexidine
      ×
      1. Leard A, Addy M. The propensity of different brands of tea and coffee to cause staining associated with chlorhexidine. J Clin Periodontol 1997;24:115-8.
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

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