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Drug

Chlorpheniramine

Common brand names:

Aller-Chlor, Chlo-Amine, Chlor-Trimeton Allergy, Efidac 24

Chlorpheniramine is an antihistamine used to relieve allergic rhinitis (seasonal allergy) symptoms including sneezing, runny nose, itching, and watery eyes. It is also used to treat immediate allergic reactions. Chlorpheniramine is available in nonprescription products alone and in combination with other nonprescription drugs, to treat symptoms of allergy, colds, and upper respiratory infections.

Summary of Interactions with Vitamins, Herbs, & Foods

Negative Interactions
1
- Chlorpheniramine
  Henbane
  Potential Negative Interaction
  Antihistamines, including chlorpheniramine, can cause “anticholinergic” side effects such as dryness of mouth and heart palpitations. Henbane (Hyoscyamus niger) also has anticholinergic activity and side effects. Therefore, use of henbane with chlorpheniramine could increase the risk of anticholinergic side effects, though apparently no interactions have yet been reported. Henbane should not be taken except by prescription from a physician trained in its use, as it is extremely toxic.
  Henbane
  Chlorpheniramine
  ×
  1. Blumenthal M, ed. The Complete German Commission E Monographs. Austin, TX: American Botanical Council, 1998, 146.

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.