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Drug

Hydralazine

Common brand names:

Apresoline

Hydralazine is a drug used to lower blood pressure in people with hypertension. Hydralazine relaxes the muscles that control the diameter of blood vessels. This relaxation allows the blood vessels to dilate (open wider), lowering blood pressure.

Summary of Interactions with Vitamins, Herbs, & Foods

Supportive Interactions
1
- Hydralazine
  Vitamin B6
  Replenish Depleted Nutrients
  This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.
  Vitamin B6 can bind to hydralazine to form a complex that is excreted in the urine, increasing vitamin B6 loss. This may lead to vitamin B6 deficiency. People taking hydralazine should consult with their doctor to discuss the possibility of vitamin B6 supplementation.
  Vitamin B6
  Hydralazine
  ×
  1. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 131-2.
  2. Raskin NH, Rishman RA. Pyridoxine-deficiency neuropathy due to hydralazine. N Engl J Med 1965;273:1182-5.

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.