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Drug

Lomotil®/Lonox®

Common brand names:

Lomotil, Logen, Lomanate, Lonox

This is a combination drug containing two ingredients, diphenoxylate and atropine, that is used in the treatment of diarrhea. Diphenoxylate is in a class of drugs known as antidiarrheals.

Summary of Interactions with Vitamins, Herbs, & Foods

Negative Interactions
2
- Atropine
  Teas and Herbs with Tannin
  Reduces Effectiveness
  Tannins are a group of unrelated chemicals that give plants an astringent taste. Herbs containing high amounts of tannins, such as green tea (Camellia sinensis), black tea, uva ursi (Arctostaphylos uva-ursi), black walnut (Juglans nigra),red raspberry (Rubus idaeus),oak (Quercus spp.), and witch hazel (Hamamelis virginiana), may interfere with the absorption of atropine taken by mouth.
  Teas and Herbs with Tannin
  Atropine
  ×
  1. Brinker F. Herb Contraindications and Drug Interactions. Sandy, OR: Eclectic Institute, 1997, 100.
- Diphenoxylate-Atropine
  Teas and Herbs with Tannin
  Reduces Effectiveness
  Tannins are a group of unrelated chemicals that give plants an astringent taste. Herbs containing high amounts of tannins, such as green tea (Camellia sinensis), black tea, uva ursi (Arctostaphylos uva-ursi), black walnut (Juglans nigra),red raspberry (Rubus idaeus),oak (Quercus spp.), and witch hazel (Hamamelis virginiana), may interfere with the absorption of the drug when taken by mouth.
  Teas and Herbs with Tannin
  Diphenoxylate-Atropine
  ×
  1. Brinker F. Herb Contraindications and Drug Interactions. Sandy, OR: Eclectic Institute, 1997, 100.

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.