Drug
Promethazine-DM
Summary of Interactions with Vitamins, Herbs, & Foods
Negative Interactions
1- Potential Negative Interaction
Promethazine
Henbane
Antihistamines, including promethazine, can cause “anticholinergic” side effects such as dryness of mouth and heart palpitations. Henbane also has anticholinergic activity and side effects. Therefore, use with promethazine could increase the risk of anticholinergic side effects, though apparently no interactions have yet been reported with promethazine and henbane. Henbane should not be taken except by prescription from a physician trained in its use, as it is extremely toxic.
HenbanePromethazine- Blumenthal M, ed. The Complete German Commission E Monographs. Austin, TX: American Botanical Council, 1998, 146.
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.