Drug
Quetiapine
Common brand names:
Seroquel, Seroquel XRQuetiapine is used to treat symptoms associated with psychiatric disorders, such as delusions, hallucinations, disorganized thinking and speech, and bizarre behavior. It is in a class of antipsychotic drugs known as dibenzapines.
Summary of Interactions with Vitamins, Herbs, & Foods
Negative Interactions
1- Potential Negative Interaction
Quetiapine
Grapefruit
Ingestion of grapefruit or grapefruit juice may increase the absorption of quietiapine by inhibiting an enzyme that breaks down the drug in the intestinal tract . Consumption of grapefruit products could therefore increase both the effectiveness and the adverse effects of this drug. People taking quietiapine should not use grapefruit products without medical supervision.GrapefruitQuetiapine- Fuhr U. Drug interactions with grapefruit juice. Extent, probable mechanism and clinical relevance. Drug Saf 1998;18:251-72.
Supportive Interactions
1- Support Medicine
Quetiapine
Glycine
This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.
In a small double-blind study, people with schizophrenia being treated with risperidone experienced an improvement in their symptoms when glycine was added to their treatment regimen. The initial amount of glycine used was 4 grams per day; this was increased gradually over a period of 10 to 17 days to a maximum of 0.8 grams per 2.2 pounds of body weight per day.
GlycineQuetiapine- Heresco-Levy U, Ermilov M, Lichtenberg P, et al. High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia. Biol Psychiatry 2004;55:165-71.