Drug
Tranylcypromine
Common brand names:
ParnateSummary of Interactions with Vitamins, Herbs, & Foods
Negative Interactions
1- Potential Negative Interaction
Tranylcypromine
Scotch Broom
This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.
Scotch broom contains high levels of tyramine. Combining phenelzine and Scotch broom may cause MAOI-type reactions (diarrhoea, flushing, sweating, pounding chest, dangerous changes in blood pressure, and other symptoms). It is important for people taking phenelzine to avoid Scotch broom. People with questions about phenelzine and Scotch broom should ask their doctor.
Scotch BroomTranylcypromine- Brinker F. Interactions of pharmaceutical and botanical medicines. J Naturopathic Med 1997;7(2):14-20.
Supportive Interactions
1- Replenish Depleted Nutrients
Tranylcypromine
Vitamin B6
This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.
Phenelzine has a chemical structure similar to other drugs (isoniazid and hydralazine) that can cause vitamin B6 deficiency. One case of phenelzine-induced vitamin B6 deficiency has been reported. Little is known about this interaction. People taking phenelzine should ask their doctor about monitoring vitamin B6 levels and considering supplementation.
Vitamin B6Tranylcypromine- Heller CA, Friedman PA. Pyridoxine deficiency and peripheral neuropathy associated with long-term phenelzine therapy. Am J Med 1983;75:887-8.