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Nutritional Supplement

Adenosine Monophosphate

Possible Deficiencies

Preliminary research suggests that people with herpes simplex or herpes zoster (shingles) infections may have low levels of AMP; however, the clinical significance of this finding is unclear.5

Side Effects

The limited number of human studies involving oral AMP have not indicated any side effects. However, some researchers have expressed concern that supplemental intake of AMP could, in theory, increase levels of adenosine, a substance related to AMP that may interfere with immune function.6 Doctors using AMP injections report that too-rapid intravenous administration or inadvertent administration of an intramuscular injection into a vein could cause life-threatening arrhythmias of the heart.7

References

1. Bernstein JE, Korman NJ, Bickers DR, et al. Topical capsaicin treatment of chronic postherpetic neuralgia. J Am Acad Dermatol 1989;21:265-70.

2. Sklar SH, Blue WT, Alexander EJ, et al. Herpes zoster. The treatment and prevention of neuralgia with adenosine monophosphate. JAMA 1985;253:1427-30.

3. Sklar SH, Wigand JS. Herpes zoster. Br J Dermatol 1981;104:351-2.

4. Gajdos A. AMP in porphyria cutanea tarda. Lancet 1974;I:163 [letter].

5. Sklar SH. Herpes virus infection. JAMA 1977;237:871-2.

6. Sherlock CH, Corey L. Adenosine monophosphate for the treatment of varicella zoster infections: A large dose of caution. JAMA 1985;253:1444-5.

7. Gaby AR, Wright JV. Nutritional Therapy in Medical Practice. Proceedings from Nutritional Therapy in Medical Practice Conference, Seattle, WA, Oct 25-8, 1996, 33; gaby@halcyon.com.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.