Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start using alprostadil and each time you get a refill. Learn all preparation and usage instructions. If you have any questions, ask your doctor or pharmacist.

This medication is used by inserting the suppository into the penis as directed by your doctor. Remove the protective cover from the applicator before inserting into the penis. The dosage is based on your medical condition and response to treatment. This medication should usually work within 5 to 10 minutes to produce an erection that lasts for about 30 to 60 minutes. Do not use more than 2 doses in a 24-hour period.

Tell your doctor if your condition lasts or gets worse (for example, the drug does not produce an erection or it becomes more difficult to get an erection).