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Drug

Aripiprazole

Pronounced

"AR-i-PIP-ra-zole"

Uses

This product is a combination of aripiprazole tablets and a patch. Each tablet has an embedded sensor, and the patch detects the signal from the tablet sensor. You will use it with a smartphone application (app). Your health care professional or caregiver will also be able to see data from the tablet sensor in a web-based portal. Aripiprazole is used to treat certain mental/mood disorders (such as bipolar disorder, schizophrenia, Tourette's syndrome, and irritability associated with autistic disorder). It may also be used in combination with other medication to treat depression. Aripiprazole belongs to a class of drugs known as atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain.

Warning

If you are using aripiprazole in combination with other medication to treat depression, also carefully read the drug information for the other medication.

There may be a slightly increased risk of serious, possibly fatal side effects (such as stroke, heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.

Other Uses

This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This medication may also be used for obsessive-compulsive disorder.

How to Use This Medication

Read the Medication Guide provided by your pharmacist before you start taking aripiprazole and each time you get a refill. Before using this product, download the smartphone app and follow all the Instructions for Use. Make sure the app works with your smartphone. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. Swallow this medication whole. Do not split, crush, or chew the tablets. The dosage is based on your medical condition, response to treatment, age, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Apply the patch when instructed to do so by the smartphone app. The patch should be applied just above the lower edge of your rib cage. Do not place the patch on skin that is scraped, cracked, or irritated. Change the placement each time so the patch is not on the same spot where the last patch was placed. Leave the patch on when showering, swimming, or exercising. The smartphone app will tell you when to change the patch (weekly or sooner). If you have skin irritation, remove the patch and tell your doctor right away. If you are going to have an MRI test, you will need to remove your patch before the test and apply a new patch afterward. (See also Precautions section.)

The tablet is usually detected by the patch and smartphone app within 30 minutes after you take it, but it could take as long as 2 hours. Sometimes the tablet might not be detected at all. If this happens, do not repeat your dose.

To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

It may take several weeks before you get the full benefit of this drug. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Keep taking this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.

Tell your doctor if your condition does not get better or if it gets worse.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

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Information expires December 2025.