Read the Medication Guide and Instructions for Use provided by your pharmacist before you start using belimumab and each time you get a refill. Ask your health care professional how to prepare and use this medication. If you have any questions, ask your doctor or pharmacist.

Inject this medication under the skin as directed by your doctor, usually once a week or once every 2 weeks. The injection is given in the thighs or abdomen (at least 2 inches from your belly button). The dosage is based on your medical condition and response to treatment. If you are switching from receiving this medication by injection into a vein, be sure you learn how and when to start using this form of belimumab.

Take the medication out of the refrigerator 30 minutes before you inject it to allow it to reach room temperature. Do not warm up this medication any other way (for example, do not heat it in the microwave, place it in hot water, or leave it in direct sunlight). Do not shake the medication. Before using, check this product for particles or discoloration. If either is present, do not use the liquid. Before injecting each dose, clean the skin you are going to inject into (the injection site) with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject into skin that is tender, bruised, red, or hard. To lessen bruising, do not rub the injection site after a shot. Learn how to store and discard medical supplies safely.

Use this medication regularly to get the most benefit from it. To help you remember, use it on the same day each week. Mark your calendar with a reminder.

Tell your doctor if your condition does not get better or if it gets worse.