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Drug

Bupropion

Pronounced

"byou-PRO-pee-on"

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: codeine, pimozide, tamoxifen, thioridazine.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication.

This medication may interfere with certain medical/lab tests (such as brain scan for Parkinson's disease, urine screening for amphetamines), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.

  • Supportive Interactions

    1

    • Bupropion

      Yohimbe

      Support Medicine

      A 50-year-old woman who was unresponsive to traditional antidepressant therapy was reported to have a marked and persistent improvement in mood when yohimbine was added to her bupropion therapy. Further research is necessary to determine the significance of this finding.

      Yohimbe
      Bupropion
      ×
      1. Pollack MH, Hamerness P. Adjunctive yohimbine for treatment in refractory depression. Biol Psychiatry 1993;33:220-1.

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