Drug
Busulfan
Pronounced
"byou-SULL-fan"
Uses
Busulfan is used as a pretreatment for patients who are undergoing stem cell transplant for chronic myelogenous leukemia (CML).
Warning
This medication decreases bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, or cause you to bruise or bleed more easily. Tell your doctor right away if you develop any of the following symptoms: signs of an infection (such as sore throat that doesn't go away, fever, chills), easy bruising/bleeding, pale skin, unusual tiredness.
Your doctor will monitor you closely while you are using this medication. Keep all medical and lab appointments.
How to Use This Medication
This medication is given by injection into a vein over 2 hours by a health care professional. It is given as directed by your doctor, usually every 6 hours. While you receive busulfan, your doctor may also prescribe other medications to help prevent seizures and nausea/vomiting caused by the medication.
The dosage is based on your weight, medical condition, lab tests, and response to treatment.