Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Other medications can affect the removal of elagolix from your body, which may affect how elagolix works. Examples include asciminib, belumosudil, cyclosporine, encorafenib, gemfibrozil, letermovir, resmetirom, vadadustat, voclosporin, among others.

This medication can speed up the removal of other medications from your body, which may affect how they work. Examples of affected drugs include daridorexant, elacestrant, mavacamten, quizartinib, revumenib, among others.

Hormonal birth control may interact with this medication. Women of childbearing age should talk with the doctor about using reliable forms of non-hormonal birth control.