Aisle7 Demo Web

Drug

Hyoscyamine

Pronounced

"hi-oh-SYE-uh-meen"

Drug Interactions

See also How to Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug are: certain azole anti-fungal drugs (ketoconazole, itraconazole), bisphosphonate drugs (such as alendronate, risedronate), corticosteroids (such as prednisone), digoxin (slow-dissolving tablets), potassium tablets/capsules, pramlintide.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

This medication may interfere with certain lab tests, possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.

Negative Interactions
2
- Hyoscyamine
  Anisodus tanguticus
  Potential Negative Interaction
  The herb Anisodus tanguticus contains a chemical that has effects similar to atropine, a compound related to hyoscyamine. Though no human studies have investigated a possible adverse interaction between hyoscyamine and anisodus, individuals should avoid the combination until more is known.
  Anisodus tanguticus
  Hyoscyamine
  ×
  1. Qicheng F. Some current study and research approaches relating to the use of plants in the traditional Chinese medicine. J Ethnopharmacol 1980;2:57-63.
- Hyoscyamine
  Iron
  Potential Negative Interaction
  Absorption of ferrous citrate, an iron compound that is usually well absorbed, is reduced in individuals taking hyoscyamine; therefore, these two substances should not be taken at the same time.
  Iron
  Hyoscyamine
  ×
  1. Orrego-Matte H, Fernandez O, Mena I. Effect of anticholinergic agents on the intestinal absorption of 59 Fe ferrous citrate. Am J Dig Dis 1971;16:789-95.