Drug
Losartan-Hydrochlorothiazide
Pronounced
"low-SAR-tan/HI-dro-klor-oh-THIGH-uh-zide"
Uses
This drug is used to treat high blood pressure. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: losartan and hydrochlorothiazide. Losartan is an angiotensin receptor blocker (ARB) and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water.
Warning
This drug can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. It is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor right away.
Other Uses
This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This drug may also be used for heart failure.
How to Use This Medication
Read the Patient Information Leaflet if available from your pharmacist before you start taking losartan/hydrochlorothiazide and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually once daily. If this medication causes you to urinate more often, it is best to take it at least 4 hours before your bedtime to prevent having to get up to urinate.
If you also take certain drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take losartan/hydrochlorothiazide at least 4 hours before or at least 4 to 6 hours after these medications.
The dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
Tell your doctor if your condition does not get better or if it gets worse (for example, your blood pressure readings remain high or increase).