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Drug

Medroxyprogesterone

Pronounced

"meh-DROX-ee-pro-JESS-tur-own"

Uses

Medroxyprogesterone is a type of hormone (progestin). This medication is similar to the progesterone that your body naturally makes. It is used to treat cancer of the uterus lining (endometrial cancer). It is also used to treat certain types of breast cancer in women after menopause. Medroxyprogesterone helps to slow down the growth of the tumors.

Warning

Very serious side effects have been reported in women after menopause who have used medroxyprogesterone along with another drug (estrogen) during combination hormone replacement therapy. Treatment can rarely cause heart disease (for example, heart attacks), stroke, serious blood clots (possibly in the lungs and legs), dementia, and breast cancer. These risks appear to depend on the length of treatment and other factors. Combination hormone therapy should be used for the shortest possible length of time at the lowest effective dose so that the benefits are obtained while the chance of serious side effects from long-term treatment is minimized. Discuss the risks and benefits of this drug during your cancer treatment with your doctor.

If you use this medication for an extended period, you should have a complete physical exam at regular intervals (for example, once a year) or as directed by your doctor. See also Notes section.

How to Use This Medication

Read the Patient Information Leaflet if available from your pharmacist before you start using this drug and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor. The dosage is based on your medical condition and response to treatment.

Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased.

It may take up to 2 to 3 months to see a response to this medication.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

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Information expires December 2025.