Drug
Mesalamine
Pronounced
"me-SAL-a-meen"
Uses
Mesalamine (also known as 5-aminosalicylic acid or mesalazine) is used to treat certain types of bowel disease (ulcerative colitis, proctosigmoiditis, proctitis). It does not cure these conditions, but it may help relieve discomfort/pain and lessen how often you have diarrhea or bloody stools. Mesalamine is an aminosalicylate anti-inflammatory drug. It works by blocking the production of certain natural substances that cause inflammation. This effect helps to decrease pain and swelling.
Other Uses
This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This drug may also be used for Crohn's disease.
How to Use This Medication
Read the Patient Information Leaflet if available from your pharmacist before you start using mesalamine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Use this medication rectally as directed by your doctor, usually once daily at bedtime. The dosage is based on your medical condition and response to treatment.
Drink plenty of fluids during treatment with this medication unless otherwise directed by your doctor. This will help prevent kidney stones.
If possible, go to the toilet and have a bowel movement before using this medication. Push the single-use applicator firmly onto the spout of the spray can. Shake the spray can well for 20 seconds. Remove the safety tab, then twist the dome top as directed. Turn the can upside down. Place one foot on a chair or stool and gently insert the applicator into your rectum. Using your index finger, push down fully on the pump dome, then slowly release it. Wait 10 to 15 seconds for the foam to be delivered. Repeat for a second spray and wait another 10 to 15 seconds. Remove the applicator and dispose of it in the provided plastic bag. Wash your hands and try not to empty your bowels until the next morning.
If you have trouble keeping in 2 sprays of foam at one time, you may separate the times you use it (for example, one spray at bedtime and another spray during the night or early in the morning). Ask your doctor or pharmacist for specific directions.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.
Tell your doctor if your condition does not get better or if it gets worse.