Drug
Metoclopramide
Pronounced
"MET-oh-KLOE-pra-mide"
Uses
Metoclopramide is used by diabetic patients who have poor emptying of their stomachs (gastroparesis). Treating gastroparesis can decrease symptoms of nausea, vomiting, and stomach/abdominal fullness. Metoclopramide works by blocking a natural substance (dopamine). It speeds up stomach emptying and movement of the upper intestines.
This drug is not recommended for use in children due to an increased risk of serious side effects (such as muscle spasms/uncontrolled muscle movements). Ask the doctor or pharmacist for details.
Warning
This medication may cause a serious movement disorder called tardive dyskinesia. In some cases, this condition may be permanent. The risk of tardive dyskinesia is increased with the longer use of the medication and the more medication that you use. The risk is also increased in older adults (especially women) and in people with diabetes. Metoclopramide comes in different forms (such as tablets, solution, injection). Do not use metoclopramide products for longer than 12 weeks. Talk to your doctor about the risks and benefits of this medication.
Tell your doctor right away if you develop any unusual uncontrolled movements (especially of the face, mouth, tongue, arms, or legs). There is no treatment for tardive dyskinesia, but in some cases the symptoms may lessen or stop once metoclopramide is stopped.
How to Use This Medication
See also Warning section.
Read the Medication Guide and Instructions for Use provided by your pharmacist before you start using metoclopramide and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Use this medication in the nose as directed by your doctor, usually 1 spray in one nostril up to 4 times daily (30 minutes before meals and at bedtime). It is usually used for 2 to 8 weeks until your gut is working well. Follow the instructions to properly prime the spray if you are using the spray for the first time or if you have not used it for 2 weeks or more. When priming the spray, make sure to spray away from your face so that the medication does not get into your eyes.
To use the spray, remove the protective cap and safety clip. Tilt your head slightly forward and carefully insert the tip of the spray nozzle into a nostril. Make sure to point the tip away from the center of your nose. Close the other nostril with the other index finger and then press down on the bottle to spray the medicine into your nostril. Breathe in gently through the open nostril and breathe out slowly through your mouth. Clean the nozzle with a clean tissue and replace the cap and safety clip.
If you are unsure if you received the full dose of the medication, do not repeat the dose. Use the next dose at the regularly scheduled time.
Because of the risk of tardive dyskinesia, do not use this drug more often, in larger doses, or for longer than directed by your doctor.
If directed, use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.
If you suddenly stop using this medication, you may have withdrawal symptoms (such as dizziness, nervousness, headaches). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used metoclopramide for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal.
Tell your doctor if your condition lasts or gets worse.