Drug
Naloxone
Pronounced
"nal-OX-one"
Uses
Naloxone is used for the emergency treatment of known or suspected opioid overdose. Serious opioid overdose symptoms may include unusual sleepiness, unusual difficulty waking up, or breathing problems (ranging from slow/shallow breathing to no breathing). Other symptoms of overdose may include very small "pinpoint" pupils, slow heartbeat, or low blood pressure. If someone has serious overdose symptoms but you are not sure if the symptoms are due to opioid overdose, give naloxone right away anyway, since lasting slow/shallow breathing may cause permanent damage to the brain or death. Since symptoms of opioid overdose may return after treatment, be sure to get medical help right away after giving the first dose of naloxone.
Naloxone belongs to a class of drugs known as opioid antagonists. It works by blocking the effects of the opioid in the brain.
How to Use This Medication
Read the Instructions for Use if available from your pharmacist before you start using naloxone and each time you get a refill. Ask your health care professional how to prepare and use this medication. If you have any questions, ask your doctor or pharmacist.
Inject this medication into a muscle or under the skin as directed by your doctor. It may also be given by injection into a vein by a health care professional. The dosage is based on your medical condition and response to treatment. Children's dosage is also based on weight.
If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. Before using, check this product for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Close family and household members should know the symptoms of an opioid overdose and be instructed on how to give naloxone if needed. Opioid overdose should be treated right away to prevent serious effects (such as brain damage). See also Uses section.
The effects of this medication are rapid but not long-lasting. After giving naloxone, get medical help right away, even if the person wakes up. If symptoms return after giving an injection, give another naloxone injection every 2 to 3 minutes. Continue to closely watch the person until emergency help is received. Tell the healthcare professional that you have given an injection of naloxone.