Tiredness, mouth/throat pain, or fast/pounding heartbeat may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: new or worsening skin itching.

Although this medication is used to treat primary biliary cholangitis (PBC), it may also cause worsening of some liver symptoms. Get medical help right away if you have symptoms such as nausea/vomiting/diarrhea that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine, black stools, vomit that looks like coffee grounds, swollen abdomen, unusual decreased urination, dizziness/lightheadedness, fever, chills, or mental/mood changes.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.