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Drug

Risedronate

Common brand names:

Actonel DR

Pronounced

"RIS-e-DROE-nate"

Uses

Risedronate is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases as you age, after menopause, or if you are taking corticosteroid medications (such as prednisone) for a long time.

This medication works by slowing bone loss. This effect helps maintain strong bones and reduce the risk of broken bones (fractures). Risedronate belongs to a class of medications called bisphosphonates.

How to Use This Medication

Read the Medication Guide, and if available, the Patient Information Leaflet if available from your pharmacist before you start taking risedronate and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or immediately after breakfast as directed by your doctor, usually once a week. Choose the day of the week that best fits your schedule and take it on the same day every week. Do not take it at bedtime or while you are still in bed.

Take this medication with at least half a glass (4 ounces/120 milliliters) of plain water. Do not take it with any other beverages. Swallow the tablet whole. Do not cut, crush, chew, or suck on it. Then stay fully upright (sitting, standing or walking) and do not lie down for at least 30 minutes.

Calcium or iron supplements, vitamins that contain minerals, and products that contain calcium/magnesium/aluminum (such as antacids, laxatives) may interfere with absorption of risedronate. Medications such as quinapril, sucralfate, and bismuth subsalicylate may also interfere with absorption. Take these products at a different time of the day from when you take risedronate. Wait at least 30 minutes after taking risedronate before you take these other products.

Take this medication regularly to get the most benefit from it. To help you remember, take it on the same day each week. Mark your calendar with a reminder. Talk to your doctor about the risks and benefits of long-term use of this medication.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

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Information expires December 2025.