Drug
Sodium Bicarbonate
Pronounced
"SO-dee-um bye-KAR-buh-nate"
Drug Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Antacids can interfere with the absorption of many other drugs. Be sure to check with your pharmacist before taking antacids with any other medication.
Supportive Interactions
2- Replenish Depleted Nutrients
Sodium Bicarbonate
Folic Acid
Folic acid is needed by the body to utilize vitamin B12. Antacids, including sodium bicarbonate, inhibit folic acid absorption. People taking antacids are advised to supplement with folic acid.
Folic AcidSodium Bicarbonate- Russell RM, Golner BB, Krasinski SD, et al. Effect of antacid and H2 receptor antagonists on the intestinal absorption of folic acid. J Lab Clin Med 1988;112:458-63.
- Replenish Depleted Nutrients
Sodium Bicarbonate
Iron
In a study of nine healthy people, sodium bicarbonate administered with 10 mg of iron led to lower iron levels compared to iron administered alone. This interaction may be avoided by taking sodium bicarbonate-containing products two hours before or after iron-containing supplements.
IronSodium Bicarbonate- O'Neil-Cutting MA, Crosby WH. The effect of antacids on the absorption of simultaneously ingested iron. JAMA 1986;255:1468-70.