Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start using sumatriptan and each time you get a refill. Ask your health care professional how to prepare and use this medication. If you have any questions, ask your doctor or pharmacist.

Inject this medication under the skin as soon as symptoms of your migraine/headache appear. The dosage is based on your medical condition and response to treatment. Before injecting each dose, clean the skin you are going to inject into (the injection site) with rubbing alcohol. This medication should never be injected into a vein or into a muscle. Also, never inject this medication through clothing.

If there is no improvement in your symptoms, do not use any more doses of this medication before talking to your doctor. If your symptoms are only partly relieved, or if your headache comes back, you may use a second injection after one hour or as directed by your doctor. Do not use more than 12 milligrams in a 24-hour period.

If your symptoms are only partly relieved or your headache returns, 2 hours after the injection you may switch to sumatriptan taken by mouth instead of using a second injection. After the initial injection you may take sumatriptan by mouth every 2 hours if needed to a maximum of 100 milligrams of tablets in a 24-hour period.

If you have never taken this medication before and you have risk factors for heart disease (see Precautions), you may need to be monitored for rare but serious side effects (such as chest pain) when you use the first dose. Your doctor may ask you to use the first dose in the office.

If you are using drugs for migraine attacks on 10 or more days each month, the drugs may actually make your headaches worse (medication overuse headache). Do not use medications more often or for longer than directed. Tell your doctor if you need to use this medication more often, or if the medication is not working as well, or if your headaches get worse.