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Drug

Topotecan

Pronounced

"TOE-poe-TEE-kan"

Uses

This medication is used to treat small cell lung cancer. It works by killing cancer cells or slowing their growth.

Warning

Topotecan decreases bone marrow function. This effect may lead to a low number of blood cells such as red cells, white cells, and platelets. A low number of blood cells can cause anemia, decrease your body's ability to fight an infection, or cause your body to bruise or bleed more easily. Tell your doctor right away if you develop any of the following symptoms: unusual tiredness, pale skin, signs of infection (such as sore throat that doesn't go away, fever, chills), easy bruising/bleeding.

Your doctor will order frequent blood tests to monitor your bone marrow function while you are taking this medication. Keep all medical and lab appointments.

How to Use This Medication

Read the Patient Information Leaflet if available from your pharmacist before you start taking topotecan and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily for 5 days. Each 5-day treatment period is called a cycle. You will usually repeat this cycle every 21 days. The dosage is based on your body size, medical condition, lab tests, and response to treatment.

Swallow the capsules whole. Do not open, crush, or chew the capsules. If the capsule contents touch your skin, wash the skin right away and completely with soap and water. If the contents get into your eyes, mouth, or nose, flush right away with water for at least 15 minutes. Consult your doctor if you have redness/burning/swelling on the area of skin the contents touched or if the contents get into your eyes.

If you vomit after taking a dose, do not take another dose at that time. Take your next dose on your usual dosing schedule.

All people should wash their hands carefully after handling this drug. Women who are pregnant or who may become pregnant should not handle this medication.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

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Information expires December 2025.