Read the Patient Information Leaflet if available from your pharmacist before you start taking trametinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once daily. Take this medication on an empty stomach, at least 1 hour before or 2 hours after a meal. Swallow the tablets whole. Do not crush or break the tablets. The dosage is based on your medical condition and response to treatment. Children's dosage is also based on weight.

If you vomit, do not take another dose to catch up. Take your next dose at the regular time.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.