Read the Patient Information Leaflet provided by your pharmacist before you start using treprostinil and each time you get a refill. Follow the illustrated directions for the proper use of this medication. If you have any questions, ask your doctor or pharmacist.

This medication comes in a single-use cartridge. Do not swallow or open the cartridges. Inhale the contents of the cartridge by mouth using the inhaler device as directed by your doctor, usually 4 times daily during waking hours, at least 4 hours apart. This medication must always be used with its own special inhaler device. Always discard your old inhaler device after 7 days of use and use a new inhaler device.

Leave the cartridges sealed in the blister card until just before use. If stored in the refrigerator, bring the cartridge and inhaler device to room temperature for 10 minutes before using. Inhale the cartridge contents as directed to make sure you inhale all of the drug. Do not shake the inhaler after placing the cartridge into the inhaler device. Be sure to inhale deeply through the mouthpiece when using this drug. Hold your breath for as long as you comfortably can. Do not exhale or blow into the inhaler device. If two or more cartridges are prescribed, use only 1 cartridge at a time. Do not get this medication on the skin. If this happens, rinse the area with water.

The dosage is based on your medical condition and response to treatment.

To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Tell your doctor if your condition does not get better or if it gets worse.