Drug
Zafirlukast
Pronounced
"za-FEER-lew-kast"
Drug Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Other medications can affect the removal of zafirlukast from your body, which may affect how zafirlukast works. An example is erythromycin, among others.
This medication can slow down the removal of other medications from your body, which may affect how they work. An example is warfarin, among others.
Negative Interactions
1- Potential Negative Interaction
Zafirlukast
White Willow
Willow bark (Salix alba) contains salicin, a substance similar to aspirin. Research has shown that aspirin significantly increases blood levels of zafirlukast, which would increase the likelihood of side effects from zafirlukast. The same thing could theoretically happen if people took willow bark along with zafirlukast, although no studies have investigated this specific interaction. People may want to avoid combining willow bark with zafirlukast due to the possibility of increased side effects.
White WillowZafirlukast- Kelloway JS. Zafirlukast: the first leukotriene-receptor antagonist approved for the treatment of asthma. Ann Pharmacother 1997;31(9):1012-21.