My Cart Find A Store

Health Condition

Endometriosis

  • Vitamin C and Vitamin E

    A combination of vitamin C and vitamin E can help lessen the pain of endometriosis.

    Dose:

    1,000 mg vitamin C and 1,200 IU vitamin E daily
    Vitamin C and Vitamin E
    ×
    In a double-blind study of women with pelvic pain presumed to be due to endometriosis, supplementation with vitamin E (1,200 IU per day) and vitamin C (1,000 mg per day) for eight weeks resulted in an improvement of pain in 43% of women, whereas none of the women receiving a placebo reported pain relief.2

  • Fish Oil

    Fish oil may reduce the severity of endometriosis, and it has been shown to improve symptoms of dysmenorrhea (painful menstruation), which may be caused by endometriosis.

    Dose:

    Refer to label instructions
    Fish Oil
    ×
     

    Animal research suggests that fish oils may reduce the severity of endometriosis,3,4 and fish oils have been shown to improve symptoms of dysmenorrhea (painful menstruation),5 which may be caused by endometriosis. Therefore, while no specific research has been done on the effects of fish oils in women with endometriosis, some health practitioners recommend several grams of fish oil per day for this condition.

  • Pine Bark Extract (Pycnogenol)

    In a preliminary study, symptoms of endometriosis gradually declined when women took Pycnogenol.

    Dose:

    60 mg per day
    Pine Bark Extract (Pycnogenol)
    ×

    In a preliminary study,6 symptoms of endometriosis gradually declined when women took 60 mg per day of Pycnogenol, which is high in flavonoids. Double-blind research is needed to confirm these findings.

  • Vitex

    Vitex is recommended either alone or in combination with other herbs, such as dandelion root, prickly ash, and motherwort, by some doctors to treat endometriosis symptoms.

    Dose:

    Refer to label instructions
    Vitex
    ×
     

    Vitex is recommended either alone or in combination with other herbs, such as dandelion root, prickly ash, and motherwort, by some doctors to treat the symptoms of endometriosis.7,8 Although vitex affects hormones that in turn affect the severity of endometriosis,9 and it may be effective for premenstrual syndrome,10 no research has tested the effect of vitex supplementation on women with endometriosis. Similarly, no other botanical medicines have been scientifically researched for treating this disease.

What Are Star Ratings
×
Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Holistic Options

According to preliminary reports, regular meetings with other endometriosis sufferers may help women with endometriosis learn about the disease and cope better with the many psychological and emotional issues that often accompany this condition.11 One preliminary study found that women who had the opportunity to speak with other women with endometriosis, as well as to meet with their physician, had a higher satisfaction with their overall care.12

Acupuncture has been reported anecdotally to help control the pain associated with some cases of endometriosis,13 but no controlled studies have confirmed this claim. One small, preliminary study found that auricular acupuncture (acupuncture of the ear) was as effective as hormone therapy in treating infertility due to endometriosis.14

References

1. Eskenazi B, Warner ML. Epidemiology of endometriosis. Obstet Gynecol Clin North Am 1997;24:235-58 [review].

2. Santanam N, Kavtaradze N, Murphy A, et al. Antioxidant supplementation reduces endometriosis-related pelvic pain in humans. Transl Res 2013;161:189-95.

3. Yano Y. Effect of dietary supplementation with eicosapentaenoic acid on surgically induced endometriosis in the rabbit. Nippon Sanka Fujinka Gakkai Zasshi 1992 Mar;44(3):282-8 [in Japanese].

4. Covens AL, Christopher P, Casper RF. The effect of dietary supplementation with fish oil fatty acids on surgically induced endometriosis in the rabbit. Fertil Steril 1988;49:698-703.

5. Harel Z, Biro FM, Kottenhahn RK, Rosenthal SL. Supplementation with omega-3 polyunsaturated fatty acids in the management of dysmenorrhea in adolescents. Am J Obstet Gynecol 1996;174:1335-8.

6. Kohama T, Herai K, Inoue M. Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. J Reprod Med 2007;52:703-8.

7. Batchelder HJ, Hudson T, Lewin A, et al. Therapeutic approaches to endometriosis. The Protocol Journal of Botanical Medicine 1996;Spring:25-60.

8. Hudson T. Women's Encyclopedia of Natural Medicine. Los Angeles: Keats Publishing, 1999:79-88.

9. Sliutz G, Speiser P, Schultz AM, et al. Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. Horm Metab Res 1993;25:253-5.

10. Lauritzen C, Reuter HD, Repges R, et al. Treatment of premenstrual tension syndrome with Vitex agnus-castus. Controlled, double-blind study versus pyridoxine. Phytomedicine 1997;4:183-9.

11. Whitney ML. Importance of lay organizations for coping with endometriosis. J Reprod Med 1998;43(3 Suppl):331-4.

12. Wingfield MB, Wood C, Henderson LS, Wood RM. Treatment of endometriosis involving a self-help group positively affects patients' perception of care. J Psychosom Obstet Gynaecol 1997;18:255-8.

13. Maciocia, G. Obstetrics and Gynecology in Chinese Medicine. New York: Churchill Livingstone, 1998:691-733.

14. Gerhard I, Postneek F. Auricular acupuncture in the treatment of female infertility. Gynecol Endocrinol 1992;6:171-81.

15. Grodstein F, Goldman MB, Ryan L, Cramer DW. Relation of female infertility to consumption of caffeinated beverages. Am J Epidemiol 1993;137:1353-60.

16. Cramer DW, Wilson E, Stillman RJ, et al. The relation of endometriosis to menstrual characteristics, smoking, and exercise. JAMA 1986;255:1904-8.

17. Signorello LB, Harlow BL, Cramer DW, et al. Epidemiologic determinants of endometriosis: a hospital-based case-control study. Ann Epidemiol 1997;7:267-74.

Copyright © 2025 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.