Ginger is well-known for alleviating nausea and improving digestion. One gram of encapsulated ginger powder was used in one study to reduce the severe nausea and vomiting associated with hyperemesis gravidarum.² This condition is potentially life-threatening and should only be treated by a qualified healthcare professional. A review of six double-blind trials concluded that ginger is probably an effective treatment for nausea and vomiting in pregnancy.³

Because ginger contains some compounds that cause chromosomal mutation in the test tube, some doctors are concerned about the safety of using ginger during pregnancy. However, the available clinical research, combined with the fact that ginger is widely used in the diets of many cultures, suggests that prudent use of ginger for morning sickness is probably safe in amounts up to 1 gram per day.⁴

In two double-blind trials, supplementation with vitamin B6 (10 or 25 mg three times per day) significantly reduced the severity of morning sickness.^5,6

In a preliminary study done in the 1930s, eight women suffering from nausea and vomiting during the first trimester (13 weeks) of pregnancy received large amounts of oral adrenal cortex extract. In most cases, vomiting stopped after three to four days.⁷ In a follow-up study, women with nausea and vomiting of pregnancy received adrenal cortex extract, usually by injection at first, followed by oral administration. More than 85% of the women were completely relieved of the problem or showed definite improvement.⁸ Since no safety data exist for use during pregnancy, adrenal extract should not be used in these situations unless supervised by a doctor.

Vitamin K and vitamin C, taken together, may provide relief of symptoms for some women. In one study, 91% of women who took 5 mg of vitamin K and 25 mg of vitamin C per day reported the complete disappearance of morning sickness within three days.⁹ Menadione was removed from the market a number of years ago because of concerns about potential toxicity. Although some doctors still use a combination of vitamin K1 (the most prevalent form of vitamin K in food) and vitamin C for morning sickness, no studies on this treatment have been done.

Vitamin K and vitamin C, taken together, may provide relief of symptoms for some women. In one study, 91% of women who took 5 mg of vitamin K and 25 mg of vitamin C per day reported the complete disappearance of morning sickness within three days.¹⁰ Menadione was removed from the market a number of years ago because of concerns about potential toxicity. Although some doctors still use a combination of vitamin K1 (the most prevalent form of vitamin K in food) and vitamin C for morning sickness, no studies on this treatment have been done.