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Nutritional Supplement

Basil

Side Effects

Although concerns have been raised about the possible cancer-causing effects of estragole, a component found in variable amounts in basil volatile oil, small amounts of basil would not seem to pose a significant threat.18 However, because some herbal books suggest that estragole may be potentially carcinogenic and has been thought to stimulate uterine contractions, some herbal experts feel it may be best for pregnant or breast-feeding women to avoid use of the herb, especially the volatile oil.19 People with serious kidney or liver damage should not use basil volatile oil internally, as they could theoretically have trouble eliminating it from their bodies. However, use of basil as a seasoning in food is unlikely to be of concern.

References

1. de Vasconcelos Silva MG, Craveiro AA, Abreu Matos FJ, et al. Chemical variation during daytime of constituents of the essential oil of Ocimum gratissimum leaves. Fitoterapia 1999;70:32-4.

2. Viseshakul D, Premvatana P, Chularojmontri V, et al. Improved glucose tolerance induced by long term dietary supplementation with hairy basal seeds (Ocimum canum Sim) in diabetics. J Med Assoc Thailand 1985;68:408–11.

3. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406–9.

4. Rai V, Mani UV, Iyer UM. Effect of Ocimum sanctum leaf powder on blood lipoproteins, glycated protein and total amino acids in patients with non-insulin-dependent diabetes mellitus. J Nutr Environ Med 1997;7:113-8.

5. Kocharatana P, et al. Clinical trial of maeng-lak seeds used as a bulk laxative. Maharaj Nakornratchasima Hosp Med Bull 1985;9:120-36.

6. Muangman V, Siripraiwan S, Ratanaolarn K, et al. A clinical trial of Ocimum canum Sims seeds as a bulk laxative in elderly post-operative patients. Ramathibodi Med J 1985;8:154-8.

7. Farnsworth NR, Bunyapraphatsara N (eds). Thai Medicinal Plants. Bangkok: Medicinal Plant Information Center, 1992:180-2.

8. Kocharatana P, et al. Clinical trial of maeng-lak seeds used as a bulk laxative. Maharaj Nakornratchasima Hosp Med Bull 1985;9:120-36.

9. Muangman V, Siripraiwan S, Ratanaolarn K, et al. A clinical trial of Ocimum canum Sims seeds as a bulk laxative in elderly post-operative patients. Ramathibodi Med J 1985;8:154-8.

10. Forster HB, Niklas H, Lutz S. Antispasmodic effects of some medicinal plants. Planta Med 1980;40:303-19.

11. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 425-6.

12. Weiss RF. Herbal Medicine. Beaconsfield, UK: Beaconsfield Publishers Ltd, 1988, 185-6.

13. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 198.

14. Grieve M. A Modern Herbal vol 1. New York: Hafner, 1967:86.

15. Nadkarni AK, Nadkarni KM. Indian Materia Medica vol 1. Bombay: Popular Prakashan, 1976:861-7.

16. Farnsworth NR, Bunyapraphatsara N (eds). Thai Medicinal Plants. Bangkok: Medicinal Plant Information Center, 1992:180-2.

17. Valnet J. The Practice of Aromatherapy. New York: Destiny Books, trans. Campbell R, Houston L, 1982:97-8.

18. McGuffin M, Hobbs C, Upton R, Goldberg A (eds). American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997:143-5.

19. Brinker F. Herb Contraindications and Drug Interactions. Sandy, OR: Eclectic Medical Publications, 1998, 33-4.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.