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Nutritional Supplement

Betaine Hydrochloride

Also indexed as:Betaine HCl, Gastric Acid, Hydrochloric Acid, Stomach Acid

  • Explanation Required

    4

    • Betaine Hydrochloride

      Dessicated Thyroid

      Needs Explanation

      The normal stomach produces hydrochloric acid, which influences the absorption of thyroid hormones. Research has shown that taking drugs that inhibit the production of stomach acid reduces the absorption of thyroid hormones. Conversely, people with low stomach acid who take betaine hydrochloride for "acid-replacement therapy" would be expected to have an increase in their absorption of thyroid hormones. For that reason, people taking thyroid hormones should not take betaine hydrochloride without the supervision of a doctor, who can determine whether a change in thyroid hormone dose is necessary.

      Dessicated Thyroid
      Betaine Hydrochloride
      ×
      1. Centanni M, Gargano L, Canettieri G, et al. Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis. N Engl J Med2006;354:1787-95.

    • Betaine Hydrochloride

      Levothyroxine

      Needs Explanation

      The normal stomach produces hydrochloric acid, which influences the absorption of thyroid hormones. Research has shown that taking drugs that inhibit the production of stomach acid reduces the absorption of thyroid hormones. Conversely, people with low stomach acid who take betaine hydrochloride for "acid-replacement therapy" would be expected to have an increase in their absorption of thyroid hormones. For that reason, people taking thyroid hormones should not take betaine hydrochloride without the supervision of a doctor, who can determine whether a change in thyroid hormone dose is necessary.

      Levothyroxine
      Betaine Hydrochloride
      ×
      1. Centanni M, Gargano L, Canettieri G, et al. Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis. N Engl J Med2006;354:1787-95.

    • Betaine Hydrochloride

      Liothyronine

      Needs Explanation

      The normal stomach produces hydrochloric acid, which influences the absorption of thyroid hormones. Research has shown that taking drugs that inhibit the production of stomach acid reduces the absorption of thyroid hormones. Conversely, people with low stomach acid who take betaine hydrochloride for "acid-replacement therapy" would be expected to have an increase in their absorption of thyroid hormones. For that reason, people taking thyroid hormones should not take betaine hydrochloride without the supervision of a doctor, who can determine whether a change in thyroid hormone dose is necessary.

      Liothyronine
      Betaine Hydrochloride
      ×
      1. Centanni M, Gargano L, Canettieri G, et al. Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis. N Engl J Med2006;354:1787-95.

    • Betaine Hydrochloride

      Liotrix

      Needs Explanation

      The normal stomach produces hydrochloric acid, which influences the absorption of thyroid hormones. Research has shown that taking drugs that inhibit the production of stomach acid reduces the absorption of thyroid hormones. Conversely, people with low stomach acid who take betaine hydrochloride for "acid-replacement therapy" would be expected to have an increase in their absorption of thyroid hormones. For that reason, people taking thyroid hormones should not take betaine hydrochloride without the supervision of a doctor, who can determine whether a change in thyroid hormone dose is necessary.

      Liotrix
      Betaine Hydrochloride
      ×
      1. Centanni M, Gargano L, Canettieri G, et al. Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis. N Engl J Med2006;354:1787-95.

References

1. Golan R. Optimal Wellness. New York: Ballantine Books, 1995, 373-4.

2. Capper WM, Butler TJ, Kilby JO, Gibson MJ. Gallstones, gastric secretion and flatulent dyspepsia. Lancet 1967;i:413-5.

3. Bray GW. The hypochlorhydria of asthma in childhood. Q J Med 1931;24:181-97.

4. Rawls WB, Ancona VC. Chronic urticaria associated with hypochlorhydria or achlorhydria. Rev Gastroenterol 1951;18:267-71.

5. Allison JR. The relation of hydrochloric acid and vitamin B complex deficiency in certain skin diseases. South Med J 1945;38:235-41.

6. Oelgoetz AW, Oelgoetz PA, Wittenkind J. The treatment of food allergy and indigestion of pancreatic origin with pancreatic enzymes. Am J Dig Dis Nutr 1935;2:422-6.

7. McCann M. Pancreatic enzyme supplement for treatment of multiple food allergies. Ann Allergy 1993;71:269 [abstract #17].

8. Kokkonen J, Simila S, Herva R. Impaired gastric function in children with cow's milk intolerance. Eur J Pediatr 1979;132:1-6.

9. Kokkonen J, Simila S, Herva R. Gastrointestinal findings in atopic children. Eur J Pediatr 1980;134:249-54.

10. Gonzalez H, Ahmed T. Suppression of gastric H2-receptor mediated function in patients with bronchial asthma and ragweed allergy. Chest 1986;89:491-6.

11. Johnson L, Eckardt R. Rosacea keratitis and conditions with vascularization of the cornea treated with riboflavin. Arch Ophthamol 1940;23:899-907.

12. Allison JR. The relation of hydrochloric acid and vitamin B complex deficiency in certain skin diseases. South Med J 1945;38:235-41.

13. Barba A, Rosa B, Angelini G, et al. Pancreatic exocrine function in rosacea. Dermatologica 1982;165:601-6.

14. Yancy KB, Lawley TJ. “Immunologically Mediated Skin Diseases.”Harrison's Online. 1999. http://www.harrisonsonline.com/hill-bin/Chapters.cgi (Jan 10, 2000).

15. Kastrup W, Mobacken H, Stockbrugger R, et al. Malabsorption of vitamin B12 in dermatitis herpetiformis and its association with pernicious anaemia. Acta Med Scand 1986;220:261-8.

16. Gawkrodger DJ, Ferguson A, Barnetson RS. Nutritional status in patients with dermatitis herpetiformis. Am J Clin Nutr 1988;48:355-60.

17. Hoffbrand AV, Douglas AP, Fry L, Stewart JS. Malabsorption of dietary folate (Pteroylpolyglutamates) in adult coeliac disease and dermatitis herpetiformis. Br Med J 1970;4:85-9.

18. Davies MG, Marks R, Nuki G. Dermatitis herpetiformis—a skin manifestation of a generalized disturbance in immunity. Q J Med 1978;47:221-48.

19. Crofton RW, Glover SC, Ewen SWB, et al. Zinc absorption in celiac disease and dermatitis herpetiformis: a test of small intestinal function. Am J Clin Nutr 1983;38:706-12.

20. Di Stefano M, Jorizzo RA, Veneto G, et al. Bone mass and metabolism in dermatitis herpetiformis. Dig Dis Sci 1999;44:2139-43.

21. Francis HW. Achlorhydria as an etiological factor in vitiligo, with report of four cases. Nebraska State Med J 1931;16(1):25-6.

22. Boero M, Pera A, Andriulli A, et al. Candida overgrowth in gastric juice of peptic ulcer subjects on short- and long-term treatment with H2-receptor antagonists. Digestion 1983;28:158-63.

23. Rubinstein E. Antibacterial activity of the pancreatic fluid. Gastroenterology 1985;88:927-32 [review].

24. Sarker SA, Gyr R. Non-immunological defense mechanisms of the gut. Gut 1990;33:1331-7 [review].

25. Boero M, Pera A, Andriulli A, et al. Candida overgrowth in gastric juice of peptic ulcer subjects on short- and long-term treatment with H2-receptor antagonists. Digestion 1983;28:158-63.

26. Rubinstein E. Antibacterial activity of the pancreatic fluid. Gastroenterology 1985;88:927-32 [review].

27. Sarker SA, Gyr R. Non-immunological defense mechanisms of the gut. Gut 1990;33:1331-7 [review].

28. Hartung EF, Steinbroker O. Gastric acidity in chronic arthritis. Ann Intern Med 1935;9:252.

29. Kokkonen J, Simila S, Herva R. Impaired gastric function in children with cow's milk intolerance. Eur J Pediatr 1979;132:1-6.

30. Gillespie M. Hypochlorhydria in asthma with specific reference to the age incidence. Q J Med 1935;4:397-405.

31. Fravel RC. The occurrence of hypochlorhydria in gall-bladder disease. Am J Med Sci 1920;159:512-7.

32. Murray MJ, Stein N. A gastric factor promoting iron absorption. Lancet 1968;1:614.

33. Russell RM, Krasinski SD, Samloff IM. Correction of impaired folic acid (Pte Glu) absorption by orally administered HCl in subjects with gastric atrophy. Am J Clin Nutr 1984;39:656.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.