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Nutritional Supplement

Bitter Melon

How to Use It

For those with a taste or tolerance for bitter flavor, a small melon can be eaten as food, or up to 3 1/3 ounces (100 ml) of a decoction or 2 ounces (60 ml) of fresh juice can be drunk per day.11 Though still bitter, tinctures of bitter melon (1 teaspoon [5 ml] two to three times per day) are also sometimes used. The amounts recommended would be appropriate for people with diabetes.

References

1. Raman A, Lau C. Anti-diabetic properties and phytochemistry of Momordica charantia L (Curcurbitaceae). Phytomed 1996;2:349-62.

2. Shivanagoudra S, Perera W, Perez J, et al. In vitro and in silico elucidation of antidiabetic and anti-inflammatory activities of bioactive compounds from Momordica charantia L. Bioorg Med Chem 2019;27:3097–109.

3. Yin R, Lee N, Hirpara H, Phung O. The effect of bitter melon (Mormordica charantia) in patients with diabetes mellitus: a systematic review and meta-analysis. Nutr Diabetes 2014;4:e145.

4. Ooi C, Yassin Z, Hamid T. Momordica charantia for type 2 diabetes mellitus. Cochrane Database Syst Rev 2012:Cd007845.

5. Peter E, Kasali F, Deyno S, et al. Momordica charantia L. lowers elevated glycaemia in type 2 diabetes mellitus patients: Systematic review and meta-analysis. J Ethnopharmacol 2019;231:311–24.

6. Cortez-Navarrete M, Martínez-Abundis E, Perez-Rubio K, et al. Momordica charantia Administration Improves Insulin Secretion in Type 2 Diabetes Mellitus. J Med Food 2018;21:672–7.

7. Inayat U, Khan R, Khalil Ur R, Bashir M. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients. Nutr J 2015;14:13.

8. Schulz V, Hänsel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. 3rd ed, Berlin: Springer, 1998, 168-73.

9. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 425-6.

10. Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 315-6.

11. Werbach MR, Murray MT. Botanical Influences on Illness. Tarzana, CA: Third Line Press, 1994, 139-41.

12. Brown DJ, Gaby A, Reichert R, Yarnell E. Phytotherapeutic and nutritional approaches to diabetes mellitus. Quart Rev Nat Med 1998;Winter:329-54.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.