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Nutritional Supplement

Bugleweed

Side Effects

Excessive intake of bugleweed by people with thyroid disease or use by healthy people may cause a potentially harmful decrease in thyroid function. Thyroid disease is dangerous and should only be treated under the supervision of a healthcare professional. However, long-term use of bugleweed is considered safe for people with hyperthyroidism.6 Bugleweed should not be taken by people with hypothyroidism. Bugleweed should also not be used during pregnancy and breast-feeding.7

References

1. Wagner H, Horhammer L, Frank U. Lithospermic acid, the antihormonally active principle of Lycopus europaeus L. and Symphytum officinale L. Arzneim Forsch 1970;20:705-12.

2. Winterhoff H, Gumbinger HG, Vahlensieck U, et al. Ednocrine effects of Lycopus europaeus L. following oral application. Arzneimittlforschung 1994;44:41-5.

3. Auf'mkolk M, Ingbar JC, Kubota K, et al. Extracts and auto-oxidized constituents of certain plants inhibit the receptor-binding and the biological activity of Graves' immunoglobulins. Endocrinol 1985;116:1687-93.

4. Wren RC, Williamson EM, Evans FJ. Potter's New Cyclopaedia of Botanical Drugs and Preparations. Essex, UK: Saffron Walden, 1988, 47-8.

5. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 98-9.

6. Weiss RF. Herbal Medicine. Beaconsfield, UK: Beaconsfield Publishers Ltd., 1988, 328-9.

7. Brinker F. Inhibition of endocrine function by botanical agents. I. Boraginaceae and Labiatae. J Naturopathic Med 1990;1:10-8.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.