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Nutritional Supplement

Fennel

  • Negative Interactions

    12
    • Fennel

      Ciprofloxacin

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Ciprofloxacin
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Ciprofloxacin in D5W

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Ciprofloxacin in D5W
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Delafloxacin

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Delafloxacin
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Gatifloxacin

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Gatifloxacin
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Gatifloxacin in D5W

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Gatifloxacin in D5W
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Gemifloxacin

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Gemifloxacin
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Levofloxacin

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Levofloxacin
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Levofloxacin in D5W

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Levofloxacin in D5W
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Moxifloxacin

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Moxifloxacin
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Moxifloxacin in Saline

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Moxifloxacin in Saline
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Norfloxacin

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Norfloxacin
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
    • Fennel

      Ofloxacin

      Reduces Effectiveness

      This interaction is based on this drug belonging to a drug class. While this drug may differ from the text and references below, drugs within this class work in a similar way and this interaction is applicable to drugs within the same class.

      Preliminary research in animals has shown that fennel (Foeniculum vulgare) may reduce the absorption of ciprofloxacin. This interaction may be due to the rich mineral content of the herb; it has not yet been reported in humans. People taking ciprofloxacin should avoid supplementing with fennel-containing products until more is known.

      Ofloxacin
      Fennel
      ×
      1. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.

References

1. Forster HB, Niklas H, Lutz S. Antispasmodic effects of some medicinal plants. Planta Med 1980;40:303-19.

2. Tanira MOM, Shah AH, Mohsin A, et al. Pharmacological and toxicological investigations on Foeniculum vulgare dried fruit extract in experimental animals. Phytother Res 1996;10:33-6.

3. Hare HA, Caspari C, Rusby HH. The National Standard Dispensatory. Philadelphia: Lea & Febiger, 1916, 63, 1129.

4. Forster HB, Niklas H, Lutz S. Antispasmodic effects of some medicinal plants. Planta Med 1980;40:303-19.

5. May B, Kuntz HD, Kieser M, Kohler S. Efficacy of a fixed peppermint/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung 1996;46:1149-53.

6. Westphal J, Hörning M, Leonhardt K. Phytotherapy in functional upper abdominal complaints. Results of a clinical study with a preparation of several plants. Phytomedicine 1996;2:285-91.

7. Madisch A, Heydenreich CJ, Wieland V, et al. Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. Arneimittlforschung 1999;49:925-32.

8. Portincasa P, Bonfrate L, Scribano ML, et al. Curcumin and fennel essential oil improve symptoms and quality of life in patients with irritable bowel syndrome. J Gastrointestin Liver Dis 2016;25:151–7.

9. Alexandrovich I, Rakovitskaya O, Kolmo E, et al. The effect of fennel (Foeniculum Vulgare) seed oil emulsion in infantile colic: a randomized, placebo-controlled study. Altern Ther Health Med 2003;9:58-61.

10. Weizman Z, Alkrinawi S, Goldfarb D, et al. Efficacy of herbal tea preparation in infantile colic. J Pediatr 1993;122:650-2.

11. Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 145-6.

12. Mills SY. Out of the Earth: The Essential Book of Herbal Medicine. Middlesex, UK: Viking Arkana, 1991, 424-6.

13. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 128-9.

14. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 128-9.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.