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Nutritional Supplement

Green-Lipped Mussel

Also indexed as:Green Lipped Sea Mussel

Where to Find It

Green-lipped mussels are found in the oceans off New Zealand. In supplement form, green-lipped mussel is available as a lipid extract or a freeze-dried powder.

How to Use It

The studies on green-lipped mussel have used 210 mg per day of the lipid extract or 1,050–1,150 mg per day of the freeze-dried powder.

References

1. Gibson SLM, Gibson RG. The treatment of arthritis with a lipid extract of Perna canaliculus: a randomized trial. Comp Ther Med 1998;6:122-6.

2. Gibson RG, Gibson SL, Conway V, et al. Perna canaliculus in the treatment of arthritis. Practitioner 1980;224L:955-9.

3. Audeval B, Bouchacourt P. Double-blind, placebo-controlled study of the mussel perna canaliculus (New Zealand green-lipped mussel) in gonarthrosis (arthritis of the knee). Gazette Med 1986;93:111-5.

4. Brooks PM. Side effects from Seatone. Med J Aust 1980;2:158 [letter].

5. Gibson RG, Gibson SLM, Conway V, Chappell D. Perna canaliculus in the treatment of arthritis. Practitioner 1980;224:955-660.

6. Audeval B, Bouchacourt P. Etude controle en double aveugle contra placebo de l'extrait de moule Perna canaliculus dans las gonarthrose. Gazette Medicale 1986;38:111-6.

7. Huskisson EC, Scott J, Bryans R. Seatone is ineffective in rheumatoid arthritis. BMJ 1981;282:1358-9.

8. Caughey DE, Grigor RR, Caughey EB, et al. Perna canaliculus in the treatment of rheumatoid arthritis. Eur J Rheumatol Inflamm 1983;6:197-200.

9. Larkin JG, Capell HA, Sturrock RD. Seatone in rheumatoid arthritis: a six-month placebo controlled study. Ann Rheum Dis 1985;44:199-201.

10. Highton TC, McArthur AW. Pilot study on the effect of New Zealand green mussel on rheumatoid arthritis. N Z Med J 1975;81:261-2.

11. Gibson SLM, Gibson RG. The treatment of arthritis with a lipid extract of Perna canaliculus: a randomized trial. Comp Ther Med 1998;6:122-6.

12. Brooks PM. Side effects from Seatone. Med J Aust 1980;2:158 [letter].

13. Emelyanov A, Fedoseev G, Krasnoschekova O, et al. Treatment of asthma with lipid extract of New Zealand green-lipped mussel: a randomised clinical trial. Eur Respir J 2002;20:596-600.

14. Brooks PM. Side effects from Seatone. Med J Aust 1980;2:158 [letter].

15. Gibson SLM, Gibson RG. The treatment of arthritis with a lipid extract of Perna canaliculus: a randomized trial. Comp Ther Med 1998;6:122-6.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.